Inicio / Gastroenterología / Abstracts de gastroenterología / Analysis of molecular alterat…

Analysis of molecular alterations in laterally spreading tumors of the colorectum

0 / 5 (0 votos)
Analysis of molecular alterations in laterally spreading tumors of the colorectum

Journal of Gastroenterology
First Online: 04 October 2016
DOI: 10.1007/s00535-016-1269-y

Tamotsu Sugai, Wataru Habano, Ryo Takagi, Hiroo Yamano, Makoto Eizuka, Noriyuki Arakawa, Yayoi Takahashi, Eiichiro Yamamoto, Keisuke Kawasaki, Syunichi Yanai, Kazuyuki Ishida, Hiromu Suzuki, Takayuki Matsumoto

Background: Colorectal laterally spreading tumors (LSTs) are classified into LST-Gs and LST-NGs, according to macroscopic findings. In the present study, we determined the genetic and epigenetic alterations within colorectal LSTs and protruding adenomas.

Methods: A crypt isolation method was used to isolate DNA from tumors and normal glands of 73 macroscopically verified colorectal LSTs (histologically defined adenomas; 38 LST-Gs and 35 LST-NGs) and 36 protruding adenomas. The DNA was processed using…

Seguir leyendo

Comentarios

Para dejar un comentario antes debes iniciar sesión:

¿No tienes una cuenta?

Regístrate a través de éste enlace.