Journal of Gastroenterology
Fecha de publicación: 09 de abril de 2018
Autores:Takeshi Sano, Keisho Chin, Hiroshi Kawachi, Daisuke Takahari, Mariko Ogura, Takashi Ichimura, Izuma Nakayama, Hiroki Osumi, Tomohiro Matsushima, Mitsukuni Suenaga, Eiji Shinozaki, Naoki Hiki, Yuichi Ishikawa, Kensei Yamaguchi.
Background: There is growing interest in the clinical significance of intratumoral HER2 heterogeneity. Its prognostic and predictive impacts on trastuzumab efficacy were demonstrated in breast cancer. However, its clinical significance in gastric cancer is still unclear.