Cancer Cell
Fecha de publicación: 10 June 2019
DOI: https://doi.org/10.1016/j.ccell.2019.05.007
Autores: Max D. Wellenstein, Karin E. de Visser
Background: Understanding how tumors escape from immune attack may offer novel therapeutic opportunities. Veglia et al. (2019) demonstrate in Nature that fatty acid transport protein 2 (FATP2) endows neutrophils with immunosuppressive capabilities that promote cancer growth. This receptor can be targeted to unleash anti-tumor immunity and to potentiate immune checkpoint blockade.
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