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Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study

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Indigo naturalis is effective even in treatment-refractory patients with ulcerative colitis: a post hoc analysis from the INDIGO study

Journal of Gastroenterology

Fecha de publicación: 16 September 2019

DOI: https://doi.org/10.1007/s00535-019-01625-2

Autores: Makoto Naganuma, Shinya Sugimoto, Tomohiro Fukuda, Keiichi Mitsuyama, Taku Kobayashi, Naoki Yoshimura, Hidehisa Ohi, Shinji Tanaka, Akira Andoh, Naoki Ohmiya, Keiichiro Saigusa, Takayuki Yamamoto, Yuichi Morohoshi, Hitoshi Ichikawa, et al.

Background: We recently reported the efficacy of indigo naturalis (IN) in patients with active ulcerative colitis (UC) in a randomized controlled trial (INDIGO study). However, few studies have been conducted to investigate whether IN is effective even in treatment-refractory cases, such as in those with steroid dependency and anti-TNF refractoriness.

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