Integrated analysis of circRNAs and mRNAs expression profile revealed the involvement of hsa_circ_0007919 in the pathogenesis of ulcerative colitis

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Integrated analysis of circRNAs and mRNAs expression profile revealed the involvement of hsa_circ_0007919 in the pathogenesis of ulcerative colitis

Journal of Gastroenterology

Fecha de publicación: 29 April 2019

DOI: https://doi.org/10.1007/s00535-019-01585-7

Autores: Tingting Wang, Ning Chen, Weixia Ren, Fangfang Liu, Fangfang Gao, Lei Ye, Ying Han, Yujun Zhang, Yulan Liu.

Background: Ulcerative colitis (UC) is characterized by chronic inflammation in the colon and epigenetic factors underlying the occurrence. Circular RNAs (circRNAs) have been under intensive focus due to the circular construct and gene-regulating functions. However, the changes and roles of circRNAs in UC remain unknown.

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