Volume 5, Issue 1, February 2017
Piero Portincasa, Leonilde Bonfrate, Ornella de Bari, Anthony Lembo, Sarah Ballou
Irritable bowel syndrome (IBS) is a chronic functional gastrointestinal disorder (FGID) and is one of the most commonly diagnosed gastrointestinal diseases. The worldwide prevalence of IBS ranges from 10% to 20% [1,2] with an estimated incidence of 1.4–1.5% according to long follow-up studies lasting 10–12 years [3, 4]. IBS is more common in women and in young adults . IBS is responsible for about one-third of all referrals to gastroenterology specialists and is associated with significant economic costs and psychosocial burden [6–8].