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Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management

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Mantle cell lymphoma: 2019 update on the diagnosis, pathogenesis, prognostication, and management

American Journal of Hematology

Fecha de publicación: 8 April 2019

DOI: https://doi.org/10.1002/ajh.25487

Autores: Preetesh Jain, Michael Wang

Background: Unprecedented advances in our understanding of the pathobiology, prognostication, and therapeutic options in mantle cell lymphoma (MCL) have taken place in the last few years. Heterogeneity in the clinical course of MCL—indolent vs aggressive—is further delineated by a correlation with the mutational status of the variable region of immunoglobulin heavy chain, methylation status, and SOX‐11 expression.

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