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Molecular subtype switching in early-stage gastric cancers with multiple occurrences

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Molecular subtype switching in early-stage gastric cancers with multiple occurrences

The Lancet Gastroenterology & Hepatology

Fecha de publicación: 21 January 2019

DOI: https://doi.org/10.1007/s00535-019-01547-z

Autores: Shinya Takaoka, Yosuke Hirotsu, Hiroshi Ohyama, Hitoshi Mochizuki, Kenji Amemiya, Toshio Oyama, Hiroshi Ashizawa, Dai Yoshimura, Keiko Nakagomi, Kenji Hosoda, Yoji Suzuki, Yuichiro Kojima, Masao Omata.

Background: Multiple gastric cancers at the same time (synchronous) or recurrence after 1 year (metachronous) are frequently encountered. Since their genetic profiles were not well elucidated, we molecularly subtyped the genetic events of synchronous and metachronous early-stage gastric cancers.

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