Non-invasive diagnosis of liver fibrosis in patients with alcohol-related liver disease by transient elastography: an individual patient data meta-analysis

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The Lancet Gastroenterology and Hepatology

Fecha de publicación: 5 july 2018

DOI: https://doi.org/10.1016/S2468-1253(18)30124-9

Autores: Prof Eric Nguyen-Khac, MD. Maja Thiele, PhD. Cosmin Voican, MD
Prof Pierre Nahon, MD. Prof Christophe Moreno, MD. Prof Jerome Boursier, MD. et al

Background: The value of transient elastography for the non-invasive diagnosis of alcohol-related liver fibrosis is subject to debate. We did an individual patient data (IPD) meta-analysis to determine specific diagnostic cutoff values for liver stiffness in alcohol-related fibrosis, and to assess the effect of aminotransferase concentrations, bilirubin concentrations, and presence of asymptomatic and non-severe alcoholic hepatitis on liver stiffness.

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