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Prognostic Value of the Detection of Lymphovascular Invasion in Hormone Receptor-Positive Early Breast Cancer in the Era of Molecular Profiling

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Prognostic Value of the Detection of Lymphovascular Invasion in Hormone Receptor-Positive Early Breast Cancer in the Era of Molecular Profiling

Oncology: International Journal of Cancer Research and Treatment

Fecha de publicación: 25 september 2018

DOI: https://doi.org/10.1159/000492429

Autores: Mutai R., Goldvaser H., Shochat T., Peretz I., Sulkes A.,Yerushalmi R. 

Background: Lymphovascular invasion (LVI) is considered a negative prognostic factor in early breast cancer, but its role in decision-making regarding adjuvant chemotherapy is unclear in the current era of molecular profiling. This study sought to evaluate the association of LVI status with the recurrence score (RS) on the multigene Oncotype DX (ODX) assay and its impact on outcome. 

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