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Risk of radiation-associated intracranial malignancy after stereotactic radiosurgery: a retrospective, multicentre, cohort study

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Risk of radiation-associated intracranial malignancy after stereotactic radiosurgery: a retrospective, multicentre, cohort study

The Lancet Oncology

Fecha de publicación: 22 november 2018

DOI: https://doi.org/10.1016/S1470-2045(18)30659-4

Autores: Amparo Wolf, PhD., Kyla Naylor, PhD., Moses Tam, MD., Akram Habibi, BSc., Josef Novotny, PhD., Prof Roman Liščák, MD., et al.

Background: A major concern of patients who have stereotactic radiosurgery is the long-term risk of having a secondary intracranial malignancy or, in the case of patients with benign tumours treated with the technique, the risk of malignant transformation. The incidence of stereotactic radiosurgery-associated intracranial malignancy remains unknown; therefore, our aim was to estimate it in a population-based study to assess the long-term safety of this technique.

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