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Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population

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Sequencing of the MHC region defines HLA-DQA1 as the major genetic risk for seropositive rheumatoid arthritis in Han Chinese population

Annals of the Rheumatic Diseases

Fecha de publicación: 1 April 2019

DOI: http://dx.doi.org/10.1136/annrheumdis-2018-214725

Autores: Jianping Guo, Tao Zhang, Hongzhi Cao, Xiaowei Li, Hao Liang, Mengru Liu, Yundong Zou, Yuanwei Zhang, Yuxuan Wang, Xiaolin Sun, Fanlei Hu, Yan Du, Xiaodong Mo, Xu Liu, Yue Yang, Huanjie Yang, Xinyu Wu, et al.

Background: The strong genetic contribution of the major histocompatibility complex (MHC) region to rheumatoid arthritis (RA) has been generally attributed to human leukocyte antigen (HLA)-DRB1

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