Inicio / Hematología / Abstracts de hematología / Stratification by MYC express…

Stratification by MYC expression has prognostic impact in MYC translocated B‐cell lymphoma—Identifies a subgroup of patients with poor outcome

0 / 5 (0 votos)
Stratification by MYC expression has prognostic impact in MYC translocated B‐cell lymphoma—Identifies a subgroup of patients with poor outcome

European Journal of Hematology

Fecha de publicación: 9 February 2019

DOI: https://doi.org/10.1111/ejh.13219

Autores: Mette Ølgod Pedersen, Anne Ortved Gang, Erik Clasen‐Linde, Marie Fredslund Breinholt, Helle Knudsen, Signe Ledou Nielsen, Tim Svenstrup Poulsen, Tobias Wirenfeldt Klausen, Estrid Høgdall, Peter Nørgaard.

Background: In patients with large B‐cell lymphoma (LBCL) according to WHO, the prognostic significance of MYC translocation is still not sufficiently clarified. We therefore aimed to investigate whether prognostication could be improved in patients with MYC translocation positive LBCL by additional stratification according to MYC and BCL2 protein expression levels or MYC translocation partner gene as well as concurrent BCL2 and/or BCL6 translocation (DH).

Leer más

Comentarios

Para dejar un comentario antes debes iniciar sesión:

¿No tienes una cuenta?

Regístrate a través de éste enlace.