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Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors

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Surface microstructures are associated with mutational intratumoral heterogeneity in colorectal tumors

Journal of Gastroenterology

Fecha de publicación: 11 june 2018

DOI: https://doi.org/10.1007/s00535-018-1481-z

Autores: Taku Harada, Eiichiro Yamamoto, Hiro-o Yamano, Hironori Aoki, Hiro-o Matsushita, Kenjiro Yoshikawa, Ryo Takagi, Eiji Harada, Yoshihito Tanaka, Yuko Yoshida, Makoto Eizuka, Akira Yorozu, Gota Sudo, Hiroshi Kitajima, Takeshi Niinuma, et al.

Background: Recent studies revealed that colorectal tumors are composed of genetically diverse subclones. We aimed to clarify whether the surface microstructures of colorectal tumors are associated with genetic intratumoral heterogeneity (ITH).

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