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What is normal and abnormal in lactose digestion?

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The Lancet Gastroenterology & Hepatology
Published
: 06 July 2017
DOI: http://dx.doi.org/10.1016/S2468-1253(17)30180-2

Benjamin Misselwitz, Mark Fox

Variations in lactose metabolism continue to fascinate patients, clinicians, geneticists, and anthropologists.1 In the small intestine of all healthy newborns, the lactose-digesting enzyme lactase is abundant. However, in most people lactase expression is strongly reduced after infancy (ie, lactase non-persistence), resulting in a limited ability to digest lactose…

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