A comparative study on pharmacokinetics and tissue distribution of 5‐hydroxy‐4‐methoxycanthin‐6‐one and its metabolite in normal and dextran sodium sulfate‐induced colitis rats by HPLC‐MS/MS

0 / 5 (0 votos)
A comparative study on pharmacokinetics and tissue distribution of 5‐hydroxy‐4‐methoxycanthin‐6‐one and its metabolite in normal and dextran sodium sulfate‐induced colitis rats by HPLC‐MS/MS

Journal of Pharmacy and Pharmacology

Fecha de publicación: 3 de Mayo de 2020

DOI: https://doi.org/10.1111/jphp.13285

Autores: Fangle Liu, Qiuyu Zhang, Chaozhan Lin, Yufeng Yao, Meiqi Wang, Changhui Liu, Chenchen Zhu

Abstract

Objective: This study aimed to investigate the existing form of 5‐hydroxy‐4‐methoxycanthin‐6‐one (PQ‐A) in vivo after oral administration and the effects on its pharmacokinetics and tissue distribution by colitis.

Leer más

Comentarios

Para dejar un comentario antes debes iniciar sesión:

¿No tienes una cuenta?

Regístrate a través de éste enlace.