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A nationwide study on inpatient opportunistic infections in patients with chronic lymphocytic leukemia in the pre‐ibrutinib era

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A nationwide study on inpatient opportunistic infections in patients with chronic lymphocytic leukemia in the pre‐ibrutinib era

European Journal of hematology

Fecha de publicación: 19 de noviembre de 2020

DOI: https://doi.org/10.1111/ejh.13553

Autores: Vilhjálmur Steingrímsson, Gauti Kjartan Gíslason, Sigrún Þorsteinsdóttir, Sæmundur Rögnvaldsson, Magnús Gottfreðsson, Thor Aspelund, Ingemar Turesson, Magnus Björkholm, Ola Landgren, Sigurdur Y. Kristinsson

Background: Opportunistic infections in chronic lymphocytic leukemia (CLL) have been described in clinical trials, single‐center studies, and case reports. We performed a nationwide study to estimate the incidence and impact of inpatient opportunistic infections. Methods: The incidence rate (IR) and incidence rate ratio (IRR) for Swedish CLL patients diagnosed 1994‐2013, and matched controls were calculated, as well as the case‐fatality ratio (CFR).

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