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A new approach to refractory gastrointestinal stromal tumours with diverse acquired mutations

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A new approach to refractory gastrointestinal stromal tumours with diverse acquired mutations

The Lancet Oncology

Fecha de publicación: June 05, 2020

DOI: https://doi.org/10.1016/S1470-2045(20)30209-6

Autores: Toshirou Nishida, Toshihiko Doi

Background: Layered double hydroxides are good vehicles to improve stability, resistance to degradation of CUR, also they are useful to improve solubility, provide a controlled release and improve the cytotoxic activity. Additionally, it was shown that the composition of the M+2 cation of LDH affects its properties and structure and that this directly influences its biological activity. The findings are important to select the composition of the encapsulation vehicle for a specific activity.

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