Journal of Pharmacy and Pharmacology
Fecha de publicación: 3 May 2019
Autores: Mohamed F. Attia, Nicolas Anton, Justine Wallyn, Ziad Omran Thierry F. Vandamme
Background: This review highlights both the physicochemical characteristics of the nanocarriers (NCs) and the physiological features of tumour microenvironment (TME) to outline what strategies undertaken to deliver the molecules of interest specifically to certain lesions. This review discusses these properties describing the convenient choice between passive and active targeting mechanisms with details, illustrated with examples of targeting agents up to preclinical research or clinical advances.