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Are There Breast Cancer Patients with Node-Negative Small Tumours, Who Do Not Benefit from Adjuvant Systemic Therapy?

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Are There Breast Cancer Patients with Node-Negative Small Tumours, Who Do Not Benefit from Adjuvant Systemic Therapy?

Oncology: International Journal of Cancer Research and Treatment
Published: June 2017
DOI: https://doi.org/10.1159/000455050

Stüber T., Novopashenny I., Diessner J., Bartmann C., Stein R., Krockenberger M., Häusler S., Janni W., Kreienberg R., Blettner M., Wöckel A., Wischnewsky M.

Objective: To identify subgroups of patients with pT1 pN0 breast cancer (BC) who might not profit from adjuvant systemic therapy (AST).
Methods: Data of 3,774 pT1 pN0 BC patients from 17 certified BC centres within the BRENDA study group were collected between 1992 and 2008 and retrospectively analysed. Uni- and multivariate analyses were…

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