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Arterial Inflammation Detected With 18F-Fluorodeoxyglucose–Positron Emission Tomography in Rheumatoid Arthritis

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Arterial Inflammation Detected With 18F-Fluorodeoxyglucose–Positron Emission Tomography in Rheumatoid Arthritis

Arthritis & Rheumatology

Published online: 1 December 2017

DOI: 10.1002/art.40345

Afshin Zartoshti MSc, Ayse Bag Ozbek MD, Jon T. Giles MD,MPH, Richard Weinberg MD, Mona Kinkhabwala MD, Sabahat Bokhari MD, Joan M. Bathon MD, Laura Geraldino-Pardilla MD.

Objectives: In addition to traditional risk factors, excess cardiovascular disease (CVD) in rheumatoid arthritis (RA) is attributed to enhanced vascular and/or systemic inflammation. In several small studies using 18F-fluorodeoxyglucose–positron emission tomography/computed tomography (18F-FDG–PET/CT) to directly assess vascular inflammation, FDG uptake was higher in RA patients than in controls. Using a substantially larger sample of RA patients, we sought to identify RA disease characteristics independently associated with vascular FDG uptake. 

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