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Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study

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Automated typing of red blood cell and platelet antigens: a whole-genome sequencing study

The Lancet Haematology

Fecha de publicación: June 2018

DOI: https://doi.org/10.1016/S2352-3026(18)30053-X

Autores: William J Lane, Connie M Westhoff, Nicholas S Gleadall, Maria Aguad, Robin Smeland-Wagman, Sunitha Vege, Daimon P Simmons, Helen H Mah, Matthew S Lebo…

Background: There are more than 300 known red blood cell (RBC) antigens and 33 platelet antigens that differ between individuals. Sensitisation to antigens is a serious complication that can occur in prenatal medicine and after blood transfusion, particularly for patients who require multiple transfusions.

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