Rheumatology Oxford Journal
Published: 08 March 2017
Arthur Kavanaugh Edward Keystone Jeffrey D. Greenberg George W. Reed Jenny M. Griffith Alan W. Friedman Katherine C. Saunders Arijit Ganguli
Objectives: To compare clinical outcomes and treatment patterns among patients with moderate vs severe RA following biologic DMARD initiation.
Methods: Biologics-naive patients with moderate to severe RA [Clinical Disease Activity Index (CDAI) >10] who initiated a biologic DMARD were selected from the Corrona registry (2001–13). CDAI, functional status [modified HAQ (mHAQ)] and patterns of drug use were compared at 1 and 2 years post-initiation between patients with moderate…