Catechol protects against iron‐mediated oxidative brain injury by restoring antioxidative metabolic pathways; and modulation of purinergic and cholinergic enzymes activities

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Catechol protects against iron‐mediated oxidative brain injury by restoring antioxidative metabolic pathways; and modulation of purinergic and cholinergic enzymes activities

Journal of Pharmacy and Pharmacology

Fecha de publicación: 09 September 2020

DOI: https://doi.org/10.1111/jphp.13352

Autores: Veronica F. Salau, Ochuko L. Erukainure, Neil A. Koorbanally, Md. Shahidul Islam

Background: This study was aimed at investigating neuroprotective effect of catechol on redox imbalance, cholinergic dysfunctions, nucleotide hydrolysing enzymes activities, and dysregulated metabolic pathways in iron‐mediated oxidative brain injury.

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