Centre effects and case-mix in early rheumatoid arthritis observational cohorts: a narrative review

Rheumatology Oxford Journal

Fecha de publicación: 6 May 2019

DOI: https://doi.org/10.1093/rheumatology/kez151

Autores: Mark Yates, Katie Bechman, Sam Norton, Elena Nikiphorou, James Galloway

Background: Observational cohort studies in early RA are a key source of evidence, despite inconsistencies in methodological approaches. This narrative review assesses the spectrum of methodologies used in addressing centre-level effect and case-mix adjustment in early RA observational cohort studies.