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Chikungunya Arthritis: Implications of Acute and Chronic Inflammation Mechanisms on Disease Management

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Chikungunya Arthritis: Implications of Acute and Chronic Inflammation Mechanisms on Disease Management

Arthritis & Rheumatology

Fecha de publicación: 29 December 2017

DOI: https://doi.org/10.1002/art.40403

Autores: Ali Zaid PhD, Patrick Gérardin MD,PhD, Adam Taylor PhD, Helen Mostafavi BSc, Denis Malvy MD,PhD, Suresh Mahalingam PhD

Background: In the past decade, arboviruses—arthropod‐borne viruses—have been the focus of public health institutions worldwide following a spate of devastating outbreaks. Chikungunya virus, an arbovirus that belongs to the alphavirus genus, is a reemerging arthritogenic virus that has caused explosive outbreaks since 2006, notably on Réunion Island, and more recently in the Caribbean, South America, India, and Southeast Asia. The severity of arthritic disease caused by chikungunya virus has prompted public health authorities in affected countries to develop specific guidelines to tackle this pathogen. 

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