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Cytogenetic landscape in 1012 newly diagnosed chronic lymphocytic leukemia

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Cytogenetic landscape in 1012 newly diagnosed chronic lymphocytic leukemia

European Journal of Hematology

Fecha de publicación: 12 September 2019

DOI: https://doi.org/10.1111/ejh.13329

Autores: Amel Senouci, Thomas Smol, Sabine Tricot, Jania Bakala, Soraya Moulessehoul, Benoît Quilichini, Dominique Penther, Charles Herbaux, Agnès Daudignon

Background: Chronic lymphocytic leukemia (CLL) stratification mainly relies on FISH markers according to Döhner’s hierarchical model which includes high‐risk FISH markers, intermediate FISH, or low‐risk FISH. Recently, complex karyotype (CK) has been demonstrated as an independent negative prognostic factor in CLL.

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