DDIT3 modulates cancer stemness in gastric cancer by directly regulating CEBPβ

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DDIT3 modulates cancer stemness in gastric cancer by directly regulating CEBPβ

Journal of Pharmacy and Pharmacology

Fecha de publicación: 19 March 2020

DOI: https://doi.org/10.1111/jphp.13243

Autores: Hai Lin, Shufang Liu, Weidong Gao, Hongyu Liu

Background: Cancer stem cells (CSCs) have been identified to correlate with the initiation and metastasis of tumours, and DNA damage‐inducible transcript 3 (DDIT3) is associated with the poor prognosis in gastric cancer (GC). However, whether DDIT3 mediates CSCs stemness in GC is still unclear.

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