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Deletion 20q12 is associated with histological transformation of nodal marginal zone lymphoma to diffuse large B‐cell lymphoma

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Deletion 20q12 is associated with histological transformation of nodal marginal zone lymphoma to diffuse large B‐cell lymphoma

American Journal of Hematology

Fecha de publicación: 5 December 2019

DOI: https://doi.org/10.1002/ajh.25694

Autores: Lei Qian, Craig Soderquist, April Schrank‐Hacker, Honore Strauser, Vanessa Dupoux, Chi Ngong Tang, Jennifer R. Smith, Ang Sun, Sonali Majumdar, Tran Nguyen, Sandy Widura, et al.

Background: The genetic and molecular abnormalities underlying histological transformation (HT) of nodal marginal zone lymphoma (NMZL) to diffuse large B‐cell lymphoma (DLBCL) are not well known. While del(20q12) is commonly deleted in myelodysplastic syndrome it has not previously been associated with DLBCL.

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