Inicio / Oncología / Abstracts de oncología / Emerging Roles for Branched-C…

Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer

0 / 5 (0 votos)
Emerging Roles for Branched-Chain Amino Acid Metabolism in Cancer

Cancer Cell

Fecha de publicación: 10 February 2020

DOI: https://doi.org/10.1016/j.ccell.2019.12.011

Autores: Sharanya Sivanand, Matthew G. Vander Heiden

Background: Metabolic pathways must be adapted to support cell processes required for transformation and cancer progression. Amino acid metabolism is deregulated in many cancers, with changes in branched-chain amino acid metabolism specifically affecting cancer cell state as well as systemic metabolism in individuals with malignancy. This review highlights key concepts surrounding the current understanding of branched-chain amino acid metabolism and its role in cancer.

Leer más

Comentarios

Para dejar un comentario antes debes iniciar sesión:

¿No tienes una cuenta?

Regístrate a través de éste enlace.