Encapsulation of curcumin into layered double hydroxides improve their anticancer and antiparasitic activity

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Encapsulation of curcumin into layered double hydroxides improve their anticancer and antiparasitic activity

Journal of Pharmacy Pharmacology, 72: 897-908

Fecha de publicación: 13 April 2020

DOI: 10.1111 / jphp.13266

Autores: Filiberto Gutiérrez‐GutiérrezCecilia Sánchez‐JiménezItzia Azucena Rangel‐CastañedaGregorio Guadalupe Carbajal‐ArízagaAdriana Macaria Macías‐LamasAraceli Castillo‐RomeroKarina Jeanette Parra‐Saavedra.

Background: Layered double hydroxides are good vehicles to improve stability, resistance to degradation of CUR, also they are useful to improve solubility, provide a controlled release and improve the cytotoxic activity. Additionally, it was shown that the composition of the M+2 cation of LDH affects its properties and structure and that this directly influences its biological activity. The findings are important to select the composition of the encapsulation vehicle for a specific activity.

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