American Journal of Hematology
Fecha de publicación: 8 october 2018
Autores: Larysa Poluben MD., Maneka Puligandla MS., Donna Neuberg ScD., Christine R. Bryke MD., Yahsuan Hsu MS., Oleksandr Shumeiko MD., Xin Yuan MD, DSc., et al.
Background: Myeloproliferative neoplasms (MPNs) driver mutations are usually found in JAK2, MPL and CALR genes, however, 10‐15% of cases are triple negative (TN). A previous study showed lower rate of JAK2 V617F in Primary Myelofibrosis (PMF) patients exposed to low doses of ionizing radiation (IR) from Chernobyl accident.