HER2 Regulates Cancer Stem Cell Activities via the Wnt Signaling Pathway in Gastric Cancer Cells

Oncology: International Journal of Cancer Research and Treatment

Fecha de publicación: November 2019

DOI: https://doi.org/10.1159/000502845

Autores: Jung D.H., Bae Y.J., Kim J.-H., Shin Y.K., Jeung H.-C.

Background: Human epidermal growth factor 2 (HER2) gene overexpression in breast carcinoma cell lines has been shown to drive mammary carcinogenesis and tumor growth and invasion through its effects on mammary stem cells.