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Immune‐mediated diseases and risk of Crohn’s disease or ulcerative colitis: a prospective cohort study

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Immune‐mediated diseases and risk of Crohn’s disease or ulcerative colitis: a prospective cohort study

Alimentary Pharmacology & Therapeutics

Fecha de publicación: 5 de diciembre de2020

DOI:

Autores: Chun‐Han Lo, Hamed Khalili, Paul Lochhead, Mingyang Song, Emily W. Lopes, Kristin E. Burke, James M. Richter, Andrew T. Chan, Ashwin N. Ananthakrishnan

Background: Although immune‐mediated diseases (IMDs) including inflammatory bowel diseases (IBDs) are known to cluster, to what extent this is due to common environmental influences is unknown.

Methods: We used data from the prospective Nurses’ Health Study II cohort (1995‐2017) to examine the effect of diagnoses of several common IMDs on subsequent risk of Crohn’s disease (CD) or ulcerative colitis (UC) using Cox proportional hazards models, adjusting for detailed diet and lifestyle confounders.

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