Irritable bowel syndrome symptoms in axial spondyloarthritis more common than among healthy controls: is it an overlooked comorbidity?

Annals of the Rheumatic Diseases

Fecha de publicación: October 2019

DOI: http://dx.doi.org/10.1136/annrheumdis-2019-216134

Autores: Johan Karlsson Wallman, Elisabeth Mogard, Jan Marsal, Kristofer Andréasson, Anna Jöud, Mats Geijer, Lars Erik Kristensen, Elisabet Lindqvist, Tor Olofsson.

Background: The link between spondyloarthritis and inflammatory bowel disease (IBD) is well-established, with 5%–10% of patients with axial spondyloarthritis (axSpA) having concurrent IBD. Beyond that, ~50%–60% display microscopic gut inflammation, and faecal calprotectin (F-calprotectin) is elevated, although neither of these findings have been clearly linked to gut symptoms. Nevertheless, >50% of patients with ankylosing spondylitis (AS) report frequent gut pain/diarrhoea.