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Low plasma protein Z levels are associated with an increased risk for perioperative bleedings

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Low plasma protein Z levels are associated with an increased risk for perioperative bleedings

European Journal of Haematology 

Fecha de publicación: 23 January 2018

DOI: https://doi.org/10.1111/ejh.13031

Autores: Clemens Hinterleitner, Klaus‐Peter Kreisselmeier, Ann‐Christin Pecher, Paul‐Stefan Mauz, Lothar Kanz, Hans‐Georg Kopp, Karl G. Jaschonek

Background: Protein Z (PZ) deficiency has been implicated both in bleeding diatheses and in thrombophilia. Considering its ambiguous nature and the conflicting clinical data so far, we set out to evaluate the impact of low PZ on perioperative bleeding in patients who underwent surgical (ENT) interventions involving a high risk of bleeding.

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