Porous Polymeric Microparticles as an Oral Drug Platform for Effective Ulcerative Colitis Treatment

Journal of Pharmaceutical Sciences

Fecha de publicación: 16 February 2019

DOI: https://doi.org/10.1016/j.xphs.2019.02.001

Autores: Xin Zhou, Qiubing Chen, Ya Ma, Yamei Huang, Shuangquan Gou, Bo Xiao.

Background: Porous microparticles (MPs) have been regarded as a promising vehicle for drug delivery. Herein, porous MPs and their counterparts (nonporous MPs) were produced by a conventional emulsion-solvent evaporation method in the presence and absence of ammonium bicarbonate, and curcumin was encapsulated into these MPs during the preparation process.