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Prognostic relevance of oxidative stress measurement in chronic lymphocytic leukaemia

27 octubre, 2017 - 1 min.

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Prognostic relevance of oxidative stress measurement in chronic lymphocytic leukaemia

European Journal of Hematology
First published: 3 August 2017
DOI: 10.1111/ejh.12918

Giovanni D’Arena, Candida Vitale, Omar Perbellini, Marta Coscia, Francesco La Rocca, Vitalba Ruggieri, Carlo Visco, Nicola Matteo Dario Di Minno, Idanna Innocenti, Vincenzo Pizza, Silvia Deaglio, Giovanni Di Minno, Aldo Giudice, Gioacchino Calapai, Pellegrino Musto, Luca Laurenti and Eugenio Luigi Iorio

Objective: To evaluate the prognostic significance of oxidative stress (OS) and antioxidant defence status measurement in patients with chronic lymphocytic leukaemia (CLL).

Methods: d-ROMs test and BAP test were evaluated at diagnosis of 165 patients with CLL and correlated with clinical-biological features and prognosis.

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