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PTEN abnormalities predict poor outcome in children with T‐cell acute lymphoblastic leukemia treated according to ALL IC‐BFM protocols

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PTEN abnormalities predict poor outcome in children with T‐cell acute lymphoblastic leukemia treated according to ALL IC‐BFM protocols

American Journal of Hematology

Fecha de publicación: 7 January 2019

DOI: https://doi.org/10.1002/ajh.25396

Autores: Bronisława Szarzyńska‐Zawadzka, Joachim B. Kunz, Łukasz Sędek, Maria Kosmalska, Katarzyna Zdon, Przemysław Biecek, Obul R. Bandapalli, Monika Kraszewska‐Hamilton, et al.

Background: Pediatric T‐cell acute lymphoblastic leukemia (T‐ALL) is an aggressive malignancy derived from T‐cell precursors and represents 10% to15% of childhood acute lymphoblastic leukemia, the most common cancer in children.

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