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Review article: the genetics of the human leucocyte antigen region in inflammatory bowel disease

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Review article: the genetics of the human leucocyte antigen region in inflammatory bowel disease

Alimentary Pharmacology & Therapeutics

Fecha de publicación: 13 September 2019

DOI: https://doi.org/10.1111/apt.15485

Autores: James J. Ashton, Katy Latham, Robert Mark Beattie, Sarah Ennis

Background: The human leucocyte antigen (HLA) complex, located at chromosome 6p21.3 is a highly polymorphic region containing the classical class I and II HLA genes. The region is highly associated with inflammatory bowel disease (IBD), largely through genome‐wide association studies (GWAS).

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