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Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population-based studies

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Role of smoking in functional dyspepsia and irritable bowel syndrome: three random population-based studies

Alimentary Pharmacology & Therapeutics

Fecha de publicación: 13 de mayo de 2021

Autores: Nicholas J. Talley, Nicholas Powell, Marjorie M. Walker, Mike P. Jones, Jukka Ronkainen, Anna Forsberg, Lars Kjellström, Per M. Hellström, Pertti Aro, Bengt Wallner, Lars Agréus, Anna Andreasson

DOI: https://doi.org/10.1111/apt.16372

Background: It is uncertain if functional dyspepsia (FD) or irritable bowel syndrome (IBS) are linked to smoking, and smoking cessation is not part of the routine advice provided to these patients. Methods: Three population-based endoscopy studies in Sweden with 2560 community individuals in total (mean age 51.5 years, 46% male). IBS (14.9%), FD (33.5%), and associated symptoms were assessed using the validated abdominal symptom questionnaire, and smoking (17.9%) was obtained from standardised questions during a clinic visit. The effect of smoking on symptom status was analysed in an individual person data meta-analysis using mixed effect logistic regression, adjusted for snuffing, age and sex.

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