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Scalable solvent‐free production of liposomes.

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Scalable solvent‐free production of liposomes.

Journal of Pharmacy and Pharmacology

Fecha de publicación: 16 de julio de 2020

DOI: https://doi.org/10.1111/jphp.13329

Autores: Swapnil Khadke, Carla B. Roces, Rachel Donaghey, Valeria Giacobbo, Yang Su, Yvonne Perrie.

Background: A major challenge faced with the manufacture of liposomes is the high volumes of organic solvents used during manufacturing. Therefore, we have implemented an organic solvent‐free production method for drug‐loaded liposomes and demonstrated its applicability with both aqueous core‐loaded and bilayer‐loaded drugs.

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