Short survival and frequent transformation in extranodal marginal zone lymphoma with multiple mucosal sites presentation

American Journal of Hematology

Fecha de publicación: 19 February 2019

DOI: https://doi.org/10.1002/ajh.25446

Autores: Juan Pablo Alderuccio, Wei Zhao, Amrita Desai, Jeremy Ramdial, Nicolas Gallastegui, Erik Kimble, Macarena I. de la Fuente, Muhammad Husnain, Joseph D. Rosenblatt, Alvaro J. Alencar, et al.

Background: Between 11 and 37% of extranodal marginal zone lymphoma (EMZL) patients present with disease involvement in multiple mucosal sites (MMS). We analyzed 405 EMZL patients seen between 1995 and 2017: 265 (65.4%) patients presented with stage I disease, 49 of 309 (15.8%) patients with bone marrow involvement, and 35 of 328 (10.7%) patients with monoclonal gammopathy (MG).