Stromal Cells Exhibit Prevalent Genetic Aberrations in Colorectal Cancer

Cancer Cell

Fecha de publicación: 14 December 2020

DOI: https://doi.org/10.1016/j.ccell.2020.11.003

Autores: Kathleen M. McAndrews, Yang Chen, Raghu Kalluri

Background: Cells within the tumor microenvironment can influence tumor progression; however, genetic alterations in stromal cell populations remain largely unexplored. In this issue, Zhou et al. combine multiomics single-cell sequencing and identify prevalent genetic alterations in colorectal cancer stromal cell populations.

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