Systematic review with meta‐analysis: effectiveness of anti‐inflammatory therapy in immune checkpoint inhibitor‐induced enterocolitis

0 / 5 (0 votos)
Systematic review with meta‐analysis: effectiveness of anti‐inflammatory therapy in immune checkpoint inhibitor‐induced enterocolitis

Alimentary Pharmacology & Therapeutics

Fecha de publicación: 13 September 2020

DOI: https://doi.org/10.1111/apt.15998

Autores: Hajir Ibraheim,Samantha Baillie,Mark A. Samaan,Hamzah Abu‐Sbeih,Yinghong Wang,Nicholas J. Talley,Michael P. Jones,Nick Powell

Background: Immune checkpoint inhibitors have revolutionised cancer treatment, but at the cost of off‐target immune‐mediated organ damage. This includes checkpoint inhibitor‐induced enterocolitis which frequently requires hospitalisation and may be life‐threatening. Empiric treatment typically includes corticosteroids and infliximab, although no large‐scale studies have confirmed their effectiveness.

Leer más

Comentarios

Para dejar un comentario antes debes iniciar sesión:

¿No tienes una cuenta?

Regístrate a través de éste enlace.