The effect of intravenous isosorbide dinitrate in acute decompensated heart failure in hospital

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The effect of intravenous isosorbide dinitrate in acute decompensated heart failure in hospital

International Journal of Clinical Pharmacy
First Online
: 03 April 2017
DOI: 10.1007/s11096-017-0459-x

Jérémy Chambord, David Attivi, Véronique Thuus, Claire Zeghmouli, Stéphane Gibaud

Background According to new recommendations for the management of acute decompensated heart failure (ADHF) in 2015, intravenous vasodilator therapy might be given as an early therapy when systolic blood pressure is normal to high (≥110 mmHg). Only 29% of patients with ADHF are treated with vasodilators without medical contraindication. Objective To evaluate the effect of the systematic use of ISDN on ADHF without contraindication especially on rehospitalization rate. Settings The 600-bed hospital (Centre Hospitalier de l’Ouest Vosgien, Neufchâteau, France). Methods This is a retrospective study with data analysed from medical records. Patients with ADHF episodes and hospitalization…

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