American Journal of Hematology
Fecha de publicación: 23 December 2017
DOI: https://doi.org/10.1002/ajh.25015
Autores: Hongxia Yan, John Hale, Julie Jaffray, Jie Li, Yaomei Wang, Yumin Huang, Xiuli An, Christopher Hillyer, Nan Wang, Sandrina Kinet, Naomi Taylor, Narla Mohandas, Anupama Narla, Lionel Blanc
Background: Studies of human erythropoiesis have relied, for the most part, on the in vitro differentiation of hematopoietic stem and progenitor cells (HSPC) from different sources. Here, we report that despite the common core erythroid program that exists between cord blood (CB)‐ and peripheral blood (PB)‐HSPC induced toward erythroid differentiation in vitro, significant functional differences exist. We undertook a comparative analysis of human erythropoiesis using these two different sources of HSPC.
Comentarios
Para dejar un comentario antes debes iniciar sesión:
¿No tienes una cuenta?
Regístrate a través de éste enlace.