Selective Sexual Dimorphisms in Musculoskeletal and Cardiopulmonary Pathologic Manifestations and Mortality Incidence in the Tumor Necrosis Factor–Transgenic Mouse Model of Rheumatoid Arthritis

Arthritis & Rheumatology

Fecha de publicación: 10 April 2019

DOI: https://doi.org/10.1002/art.40903

Autores: Richard D. Bell MS., Emily K. Wu MS., Christopher A. Rudmann BS., Megan Forney BS., Claire R. W. Kaiser BS., Ronald W. Wood PhD., Joe V. Chakkalakal PhD., Nicole D. Paris PhD., et al.

Background: To examine and quantify the sexual dimorphism in pathologic features manifested in the musculoskeletal and cardiopulmonary systems and incidence of mortality in the tumor necrosis factor–transgenic (TNF‐Tg; Tg3647 strain) mouse model of inflammatory erosive arthritis.